IRREDUCIBLY COMPLEX: THE CLOTTING CASCADE The function of the blood clotting system is to prevent the escape of blood from a damaged vessel. To do this, the blood has a special and very complex repair procedure in place. Once initiated by a cut, the first component in the process is activated, which in turn activates the next component, and so on, in a series of cumulative, mutually-dependent steps. This physiological chain of production, or cascade, results in the formation of a solid obstruction (a clot) in order to seal over the damage. Some of the main components of the clotting cascade are the proteins fibrinogen, prothrombin, Stuart (anti-hemophilic) factor and proaccelerin. None of these are used for any other purpose in the blood. The system is very finely tuned to result in a repair process that achieves just the repair needed at just he right place and time to stop bleeding and begin the process of healing. Importantly, the process is also self-limiting to ensure that coagulation (clotting) of the entire blood supply does not occur. The Intelligent Design advocate Michael Behe, in his book Darwin’s Black Box, has noted that the clotting cascade is an example of irreducible complexity. The removal or degradation of just one, any one, of the components or steps would cause the cascade to fail. Obviously this would have dire consequences for the organism. It is exceedingly difficult to see how the clotting cascade could have volved, as any postulated simplified or ‘primitive’ version of the process would result in failure.1 Behe, M., Darwin’s Black Box, The Free Press, New York, USA, pp. 74–97, 1996. Available creation.com/store. 1. See also Behe, M., In defense of the irreducibility of the blood clotting cascade: Response to R. Doolittle, K. Miller and K. Robison, www.trueorigin.org/behe03.asp, 2000.
Other Countries (Use Australian address) Australia USA South New Europe Africa Canada Zealand $75 R500 R700 $107 $150 $75 $105 $105 $88 $128 2 yrs 3 yrs 1 yr $39 $39 £ 22 R260 $59 $39 (Pay via international money order or credit card in Australian dollars.) $46 $105 $147 $55 $75 $105 £ 39 £ 54 UK/ Singapore Use mailing address on p. 2 or visit CREATION.com/sub 3 issues per year, each over 100 pages SUBSCRIBE TODAY! As Christians we should aim to attain a higher standard than the world. The process of peer-review (“iron sharpening
iron”) is such an important biblical injunction. That’s why we believe Journal of Creation is such a valuable contribution
to Bible/science apologetics. Even though Journal of Creation often publishes ne w, groundbreaking creationist
research, all papers have been through a thorough critiquing process before they see the light of day.
Discussions in the current edition include: How discoveries on valley erosion falsify original assumptions about ‘deep time’. ; How scientific observations led astronomer Allan Sandage from atheism to Christianity. ; New cladistics analyses further demolish dinosaur to bird theories of evolution. ; How some modern maps can reveal the sequence of events during Noah’s Flood. ; How new research suggests the gene PRDM9 might be involved in rapid genetic changes. ; Critiques on the latest book releases and much more! ; Journal of Creation. See page 2.
©iSt kP oc hotocom/QUILLE .
Creation 33 ( 3) 2011